Assessment of Hematological Parameters among Malaria Patients in River Nile State, Sudan
*Corresponding author: Mosab Nouraldein Mohammed Hamad
Assistant Professor, Microbiology department, Faculty of Medicine, Elsheikh Abdallah Elbadri University, Sudan.
Corresponding Email: musab.noor13@gmail.com ,
ABSTRACT
Background: Malaria, which is responsible for a substantial number of deaths in endemic countries, has been shown to have both direct and indirect effects on the hematological parameters, notwithstanding, some hematological parameters among populations living in malaria-endemic regions have not been described consistently, as a standard for measuring malaria burden. Malaria causes a febrile illness with several changes in blood cell parameters. Some of these changes include leucopenia, thrombocytopenia, and anemia. If these changes could be correlated with the degree of parasitemia, it can serve as a guide to physicians when treating malaria. Objectives: This study was therefore aimed at the assessment of Hematological Parameters among malaria patients in River Nile State, Sudan. Methods: A total of 100 participants were in this study, 50 were malaria patients and 50 were healthy for comparison. The mean age of the study group was 40 and the control group was 45. Results: This study shows total WBCs, lymphocyte, Mixed, unaffected by malaria parasite (P. value: 0.753, 0.666, 0.131) respectively, there were significant elevations in neutrophil count (P. value 0.04). There was no significant association between RBCs, HGB, HCT, MCV, MCH, MCHC, RDW-SD, RDW-CV, and malaria (P. value: 0.409, 0.112, 0.438, 0.698, 0.773, 0.816, 0.355, 0.530) respectively. There was no significant association between PLT, PDW, MPV, PCT, and malaria (P. value: 0.894, 0.956, 0.611, 0.902) respectively. Conclusion: This study revealed that routinely used laboratory findings such as hemoglobin, leukocytes, platelet counts, and even red cell distribution width values can provide a diagnostic clue in a patient with acute febrile illness in endemic areas, thus increasing the probability of malaria and enhance prompt initiation of treatment.
