Estimation of Coagulation Test, Platelet Count, and Platelet Indices among Polycythemic Patients at Khartoum State – Sudan

Raheeg Hamza M. Hamed¹, Albaraa Abdulfatah Mohammed², Ghanem Mohammed Mahjaf², Tibyan Abd Almajed Altaher³, Mosab Nouraldein Mohammed Hamad^4*

¹Department of Haematology and Immunohematology, Faculty of Medical Laboratory Sciences,National University, Sudan.

²Associate professor, Hematology Department,  Alfajr College for science and Technology, Sudan

³Department of Medical Microbiology, Faculty of Medical Laboratory Sciences, Shendi University, Shendi, Sudan.

⁴Department of Clinical Chemistry, Faculty of Medical Laboratory Sciences, Shendi University, Sudan.

⁵Assistant professor, Microbiology department, Faculty of Medicine, Elsheikh Abdallah Elbadri University, Sudan.

Corresponding Email: mosab@eaeu.edu.sd

Abstract:

Background: An increase in the total body red cell volume (Polycythemia) directly affects coagulation parameters because of high PCV, the thrombophilic tendency tends toward thrombophilia. Aim: This study aimed to estimate the coagulation profile, platelets count, and platelet indices and correlate the parameter result among polycythemia Sudanese patients. Methods: It was an analytical comparative case-control study conducted in Alzaitona Hospital, Khartoum, from the period January to March 2023 on a total of one hundred venous blood samples collected equally from polycythemia patients (case group) and healthy (control group), then for both group complete haemogram was done using an automated cell counter (SysmexKX-2IN) and coagulation automation (New 2008 STAGO Start4). Results: The result shows normal platelets while there is prolonged prothrombin time and activated partial thromboplastin time. Conclusion: the thrombophilic tendency tends toward thrombophilia among polycythemic patients in Khartoum state.

Keywords: Polycythemic Patients, Coagulation Test, Platelet Count, Sudan.